ADC ZLM

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Brand: ADC

ADC ZLM, also known as Automatic Density Control for Zea-Lyzate Mix (ZLM), is a process used in the purification of recombinant proteins during downstream processing. It combines density gradient ultracentrifugation with automated and continuous density measurement to separate protein Millipore chromatography fractions based on density differences, which is a crucial step in protein purification. By continuously monitoring the concentration and density of a protein solution, the system can automatically adjust the density and recover protein of interest while removing impurities, thereby reducing the amount of process development time and cost required for conventional density gradient separation techniques. ADC ZLM offers a new level of control and efficiency in the purification process, achieving higher purity with shorter gradients and smaller volumes of media.